Research and Reports

Any natural product that has been around for hundreds of years and has the interest of scientists at universities around the world will have decades of research behind it. Stevia is backed by volumes of independent research. Global regulatory approvals have been possible because of the rich history of global safety studies and also some modern research.

Research Program

Below are some of the expert reviews confirming the safety behind Truvía® stevia leaf extract:

European Food Safety Authority (EFSA)

Reviewed safety of steviol glycosides.

Expert panel’s Scientific Opinion officially published on April 14, 2012 and approval granted in November 2011.

Food and Chemical Toxicology

Published safety studies conducted with rebiana.

Food and Drug Administration

Issued no-objection letter for rebiana affirmed as Generally Recognized as Safe (GRAS); FDA has responded to multiple separate GRAS notifications to date.

GRAS (Generally Recognized As Safe) Independent Expert Panel

Critically reviewed steviol glycosides database of studies along with dozens of safety studies published since ~1960.

Concluded the ingredient safe for general purpose use as a sweetener.

Health Canada

Reviewed safety of steviol glycosides and considered it safe for consumption in specified foods by the general population.

Joint FAO/WHO Expert Committee on Food Additives (JECFA)

Comprehensively examined the safety data and set a permanent ADI for steviol glycosides.

U.S. Toxicology Forum Panel Multi-stakeholder Symposium

Reviewed safety of rebaudioside A to allow for discussion by senior toxicologists in academia, industry and government.

If you have any additional questions about the research behind Truvía® natural sweetener or for a copy of the stevia leaf extract safety research published in Food and Chemical Toxicology, please contact


Erythritol Information

Erythritol is a natural, non-caloric bulking agent and sweetener produced by fermentation. It is found naturally in small amounts in several fruits such as pears, melons, and grapes as well as fermented foods such as wine and cheese.

It is used as an ingredient to provide bulk and a sugar-like crystalline appearance for Truvía® natural sweetener. Since stevia leaf extract is a high-intensity sweetener, only extremely small quantities are required to provide sweetness similar to sugar. Erythritol is used to add bulk so that Truvía® natural sweetener is easy for consumers to use. In addition, erythritol does not promote tooth decay.

Erythritol is different from other sugar alcohols in two ways:

Erythritol is not broken down by the body, so it cannot provide calories or affect blood sugar. Other sugar alcohols can be broken down by the body to varying degrees. This means that the body can use them for calories. Erythritol is different, it provides zero calories and has zero net carbs.

Erythritol has excellent gastrointestinal tolerance. While other sugar alcohols are sometimes associated with laxative side effects such as diarrhea or loose stools, erythritol is handled by the body differently. This is because most of the erythritol consumed (up to 90%) is absorbed from the small intestine. Once it is absorbed, it is no longer available for laxative effects in the lower digestive tract.


Dental Information

A study, presented at the International Association for Dental Research General Sessions of July 2010, reports that Truvía® stevia leaf extract, the calorie-free sweetener purified from the leaf of the stevia plant in an aqueous solution, does not lower dental plaque pH.

The study also reported stevia leaf extract is less acidogenic than sucrose (saccharose) solutions and comparable to the currently marketed non-sugar sweetener, sucralose12.

Download the abstract

Erythritol, which is used to provide bulk in the Truvía® natural sweetener tabletop product, is also tooth friendly. Erythritol is not converted to acids by bacteria in the mouth. Therefore, it doesn't promote tooth decay. The FDA authorized the use of the "does not promote tooth decay" health claim for erythritol. The American Dental Association adopted a position statement recognizing the role of sugar-free foods and medications in maintaining good oral health.


Important Dates and Events for Truvía® Sweetener

May 2008

Cargill’s stevia leaf extract research program published in Food and Chemical Technology.

December 2008

FDA issued no-objection letter affirming and supporting the safety of Truvía® stevia leaf extract (rebaudioside A). Official, Truvía® stevia leaf extract has Generally Recognised as Safe (GRAS).

December 2008

Truvía® natural sweetener was launched and widely available in retail in the United States. Coca-Cola introduced Sprite Green®, sweetened with Truvía® stevia leaf extract.

September 2009

French national approval granted for the use of rebaudioside A in food and beverages for up to two years published in the Official Journal of France.

April 2010

European Food Safety Authority published Scientific Opinion confirming that steviol glycosides, sweeteners extracted from the stevia plant, are safe for use in foods and beverages.

April 2010

Coca-Cola launched Fanta Still®, the first Coca-Cola product in France sweetened with Truvía® stevia leaf extract.

March 2011

Truvía® calorie-free sweetener launched in France.


Regulatory Approval of steviol glycosides in the European Union.


Stevia-based products are launched in Europe.